What is known about sweating during treatment

Sweating is listed as a possible isotretinoin side effect, but available medicine information does not say how often it occurs.

A small 1988 study found no clinically apparent change and no statistically significant average increase in stimulated sweating.

What to do if you are sweating more on Accutane

Tell the clinician who prescribes your Accutane if the sweating is severe, does not go away, or is unusual for you. Do not take more or less isotretinoin than prescribed.

When you contact the clinic, explain when the sweating began, whether it happens at rest or during sleep, where it occurs, and whether another medicine or health change appeared around the same time. A clear timeline helps the prescriber consider isotretinoin, other medicines, and health changes as possible contributors.

Excessive sweating can have more than one cause. Overactive nerves, another health condition, or a medicine may be involved. A clinician can assess the pattern and decide whether you need further evaluation.

When to get urgent help

U.S. medicine information lists chest pain, trouble breathing, fainting, a fast or pounding heartbeat, and fever separately from sweating as serious symptoms that require an immediate call to a doctor or emergency medical treatment. Do not wait for a routine message if any of those symptoms occur during isotretinoin treatment.

Frequently asked questions

Is sweating a listed side effect of isotretinoin?

Yes. Sweating is listed among possible isotretinoin side effects, although the source does not provide a frequency.

Does more sweating mean I have hyperhidrosis?

Not necessarily. Hyperhidrosis is excessive sweating that can happen even when the body does not need cooling. Medicines and health conditions can also cause excessive sweating, so a clinician may need to assess the pattern.

Should I stop Accutane if I am sweating more?

Do not change your prescribed dose on your own. Tell your prescriber if the sweating is severe, does not go away, or is unusual, and get urgent help for the warning symptoms above.

Sources

  1. MedlinePlus — Isotretinoin Drug InformationMedlinePlus, U.S. National Library of Medicine
  2. Effect of Isotretinoin on Eccrine Gland FunctionThe British Journal of Dermatology (PubMed record)
  3. Hyperhidrosis: FAQsAmerican Academy of Dermatology